Lyon or Lyons (UK: , US: , French: ljɔ̃; Arpitan: Liyon, pronounced [ʎjɔ̃]) is the third-largest city and second-largest urban area of France. It is located at the confluence of the rivers Rhône and Saône, about 470 km (292 mi) southeast of Paris, 320 km (199 mi) north of Marseille and 56 km (35 mi) northeast of Saint-Étienne. Inhabitants of the city are called Lyonnais (masculine) and Lyonnaises (feminine).

The City of Lyon proper had a population of 516,092 in 2017 within its small municipal territory of 48 km2 (19 sq mi), but together with its suburbs and exurbs the Lyon metropolitan area had a population of 2,323,221 that same year, the second-most populated in France. Lyon and 58 suburban municipalities have formed since 2015 the Metropolis of Lyon, a directly elected metropolitan authority now in charge of most urban issues, with a population of 1,385,927 in 2017. Lyon is the prefecture of the Auvergne-Rhône-Alpes region and seat of the Departmental Council of Rhône (whose jurisdiction, however, no longer extends over the Metropolis of Lyon since 2015).

Former capital of the Gauls at the time of the Roman Empire, Lyon is the seat of an archbishopric whose holder bears the title of Primate of the Gauls. Lyon became a major economic hub during the Renaissance. The city is recognised for its cuisine and gastronomy, as well as historical and architectural landmarks; as such, the districts of Old Lyon, the Fourvière hill, the Presqu'île and the slopes of the Croix-Rousse are inscribed on the UNESCO World Heritage List. Lyon was historically an important area for the production and weaving of silk. Lyon played a significant role in the history of cinema: it is where Auguste and Louis Lumière invented the cinematograph. It is also known for its light festival, the Fête des Lumières, which begins every 8 December and lasts for four days, earning Lyon the title of "Capital of Lights".

Economically, Lyon is a major centre for banking, as well as for the chemical, pharmaceutical and biotech industries. The city contains a significant software industry with a particular focus on video games; in recent years it has fostered a growing local start-up sector. Lyon hosts the international headquarters of Interpol, the International Agency for Research on Cancer, as well as Euronews. According to the Globalization and World Rankings Research Institute, Lyon is considered a Beta city, as of 2018. It ranked second in France and 40th globally in Mercer's 2019 liveability rankings.

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