Michael Santiago Render (born April 20, 1975), better known by his stage name Killer Mike, is an American rapper, actor, and activist. Mike made his debut on Outkast's 2000 LP Stankonia, and later appeared on their Grammy-winning single "The Whole World" from their greatest hits album Big Boi and Dre Present... Outkast (2001). He has since released five full-length albums as a solo artist. He is the founder of Grind Time Official Records, which he launched through SMC and Fontana Distribution.

In December 2008, Mike signed to fellow Atlanta-based rapper T.I.'s Grand Hustle Records. In 2012, he released R.A.P. Music, produced entirely by rapper and producer El-P. Killer Mike and El-P subsequently formed the duo Run the Jewels in 2013; they were signed to Fool's Gold Records and released their self-titled debut in June of that year.

Mike is also known as a social and political activist, focusing on subjects including social inequality, police brutality, and systemic racism. In addition to addressing themes of racism and police brutality in his music, he has also delivered several lectures at colleges and universities, written about social justice topics for publications such as Billboard, and been the subject of interviews regarding police misconduct and race relations. He was a visible and vocal supporter of Bernie Sanders' 2016 U.S. presidential campaign, refusing to support Hillary Clinton after Sanders left the race, and again supporting Sanders in his 2020 presidential campaign.

Mike has appeared in films such as Idlewild, Baby Driver, and ATL. The documentary series Trigger Warning with Killer Mike, in which he explores issues in the U.S. that affect the black community, premiered on Netflix in January 2019.