KSM may refer to:

Kernel same-page merging, sharing identical computer memory pages among processes

Khalid Sheikh Mohammed, terrorist held at Guantanamo Bay

Kothagudem School of Mines, later University College of Engineering, Kakatiya University

Kommando Spezialkräfte Marine, special forces of the German Navy

Komunistický svaz mládeže (Communist Youth Union), youth wing of the Communist Party of Bohemia and Moravia

Kerr Sulphurets Mitchell, an active mine exploration project 65 km northwest of Stewart, British ColumbiaKSM may also be:

KSM (band), an American all girl rock band

KSM, alternative callsign of public coast radio station KPH

KSM, IATA and FAA code for St. Mary's Airport (Alaska)

KSM, ICAO callsign for Kosmos Airlines

KSM series of microphones made by Shure