KSM may refer to:
Kernel same-page merging, sharing identical computer memory pages among processes
Khalid Sheikh Mohammed, terrorist held at Guantanamo Bay
Kothagudem School of Mines, later University College of Engineering, Kakatiya University, India
Kommando Spezialkräfte Marine, special forces of the German Navy
Komunistický svaz mládeže or Communist Youth Union, the youth wing of the Communist Party of Bohemia and Moravia
Kerr Sulphurets Mitchell, an active mine exploration project in British Columbia
KSM (band), an American all girl rock band
KPH (radio station), by alternative callsign
St. Mary's Airport (Alaska), by airport code
Kosmos Airlines, by airline code
KSM, a series of microphones by Shure